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The Jacob Bigelow papers, 1770-1879 (inclusive), 1800-1879 (bulk), contain correspondence with Jacob Bigelow's (1786-1879) colleagues concerning botanical specimens, publication of the Pharmacopoeia of the United States from 1820 to 1831, and general medical matters. There is also correspondence with his family, including his parents, siblings, and his son, physician Henry Jacob Bigelow (1818-1890).
The John Denison Hartshorn papers, 1754-1786 (inclusive), undated, contain medical notes and patient cases recorded by John Denison Hartshorn (1736-1756) while he was apprenticed to Boston physician and apothecary shop owner Silvester Gardiner (1708-1786), in addition to poetry written by Hartshorn. There is also some correspondence and papers of other physicians and associates of Hartshorn and Gardiner.