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The Henry Jacob Bigelow papers, 1840s-1856 (inclusive), 1848-1855 (bulk), principally consist of draft and final or close to final draft medical illustrations, some accompanied by case or specimen notes. Drawings are in pencil, ink, and watercolor. Subjects include a wide variety of pathological conditions, mostly tumors, including epitheliomas, cheloids, cysts, and cancerous growths.
The Jacob Bigelow papers, 1770-1879 (inclusive), 1800-1879 (bulk), contain correspondence with Jacob Bigelow's (1786-1879) colleagues concerning botanical specimens, publication of the Pharmacopoeia of the United States from 1820 to 1831, and general medical matters. There is also correspondence with his family, including his parents, siblings, and his son, physician Henry Jacob Bigelow (1818-1890).